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TOPROL-XL is a once-a-day beta-blocker for high blood
pressure, angina pectoris over the long term, and heart failure. In heart failure,
TOPROL-XL is used to treat stable, symptomatic patients with Class II or III
heart failure, as defined by the New York Heart Association classification,
that is caused by high blood pressure, blocked heart arteries, or other heart
muscle disorders. Important Product Information
- TOPROL-XL (metoprolol succinate) extended-release tablets
is used to treat high blood pressure, angina pectoris over the long term,
and heart failure. In heart failure, TOPROL-XL is used to treat stable, symptomatic
patients with Class II or III heart failure, as defined by the New York Heart
Association classification, that is caused by high blood pressure, blocked
heart arteries, or other heart muscle disorders. It was studied in patients
who were already taking other medications for heart failure. - TOPROL-XL should not be taken by people with the following
- Extreme slowing of the heart rate (known as severe bradycardia)
- A sudden and severe drop in the blood pressure and blood flow through the
body because the heart is not pumping normally (also known as cardiogenic
shock) - Uncontrolled heart failure (known as decompensated heart failure)
- A slowdown of the heart’s electrical signal (also known as heart block)
as it travels through the heart causing a slower heart rate. There are different
types or degrees of slowdown. TOPROL-XL should not be taken by patients who
have second-degree or third-degree (complete) heart block - Damage to the heart’s natural pacemaker that causes the heart to beat too
fast or too slow [unless a pacemaker device is in the body] (also known as
sick sinus syndrome) - An allergy to TOPROL-XL or any of its ingredients
In some patients, TOPROL-XL should be used with caution: those
with asthma or asthma-like lung disease or those who are taking certain calcium
channel blockers, have diabetes, overactive thyroid disease, hardening or constriction
of the arteries in the arms or legs, or are planning to have surgery.
Talk to your doctor about your health history, and be sure to tell your doctor
if you are taking TOPROL-XL or any other medications.
Until you know how you will react to TOPROL-XL, avoid activities that require
alertness.
In clinical trials of patients with high blood pressure and angina pectoris,
the most commonly reported side effects with immediate release metoprolol tartrate
are: tiredness (10%), dizziness (10%), depression (5%), diarrhea (5%), itching
or rash (5%), shortness of breath (3%), and slow heart rate (3%). If you experience
any of these or other side effects, contact your doctor.
If you’ve been diagnosed with heart failure, high blood pressure (hypertension),
or angina pectoris (chest pain), your doctor may prescribe once-a-day TOPROL-XL
to help you manage your condition. TOPROL-XL is used to treat
high blood pressure, angina pectoris over the long term, and heart failure.
In heart failure, TOPROL-XL is used to treat stable, symptomatic patients with
Class II or III heart failure, as defined by the New York Heart Association
classification, that is caused by high blood pressure, blocked heart arteries,
or other heart muscle disorders. It was studied in patients who were already
taking other medications for heart failure.
